SynCardia Total Artificial Heart (TAH) patients are effectively heart transplant recipients with four mechanical valves. They have a near-normal CVP, normal physiology and the source of their heart failure has been eliminated through biventricular replacement. In addition, there are no inotropes or anti-rejection medications needed.
TAH patients benefit from high cardiac output, typically 7 L/min ±1 for the 70cc TAH (max: 9.5 L/min) and 5 L/min ±1 for the 50cc TAH (max: 7.5 L/min). When patients exercise, there is never a need to adjust the driver settings, as cardiac output will change based on the patient’s activity level.
1 Yaung J, Arabia FA, Nurok M. Perioperative Care of the Patient With the Total Artificial Heart. Anesthesia & Analgesia. 2017;124(5):1412-1422. doi:10.1213/ane.0000000000001851.
2 Maymi MA, Gupta D, Barras WE, et al. Pediatric Mechanical Circulatory Support. Journal of Pediatric Critical Care. 2014;1(3):190.