Publications

Below is a selection of recently published journal articles about or related to the SynCardia temporary Total Artificial Heart (TAH-t). We will continue to update this page as new articles are published.

Total artificial heart in a pediatric patient is a rarity, first for Columbia Surgeons. Columbia University Irving Medical Center. (2023, April 11). https://www.cuimc.columbia.edu/news/total-artificial-heart-pediatric-patient-rarity-first-columbia-surgeons

Picard Medical and its subsidiary, Syncardia Systems, a pioneer in total artificial heart technology, to become a publicly traded company via merger with Altitude Acquisition Corp.. SynCardia. (n.d.). https://syncardia.com/news/picard-medical-and-its-subsidiary-syncardia-systems-a-pioneer-in-total-artificial-heart-technology-to-become-a-publicly-traded-company-via-merger-with-altitude-acquisition-corp/

Total artificial heart revolutionizes heart transplant surgery - advances in cardiology and heart surgery, transplantation, and pediatric cardiology. NewYork-Presbyterian. (n.d.). https://www.nyp.org/advances/total-artificial-heart-revolutionizes-heart-transplant-surgery

Saudi Arabia successful in first-ever Syncardia Total Artificial Heart ... (n.d.). https://www.zawya.com/en/business/healthcare/saudi-arabia-successful-in-first-ever-syncardia-total-artificial-heart-transplant-j31als3i

Coyan, G. N., Huckaby, L. V., Diaz‐Castrillon, C. E., Miguelino, A. M., & Kilic, A. Trends and outcomes following total artificial heart as bridge to transplant from the UNOS database. Journal of Cardiac Surgery, 37(5), 1215–1221. https://doi.org/10.1111/jocs.16329

F., Wisotzkey, & Dr. Wisotzkey is a pediatric heart failure/transplant cardiologist who specializes in the care of children with heart failure. (2022, February 9). Bright futures. Phoenix Children’s Hospital. https://www.phoenixchildrens.org/blog/2022/02/two-exciting-new-technologies
Lind, T. (2022, May 25). In the driver’s Seat: Total artificial heart recipient receives two donated organs. Spokesman.com. https://www.spokesman.com/stories/2022/may/26/in-the-drivers-seat-total-artificial-heart-recipie/

Carrier, M., Moriguchi, J., Shah, K., Anyanwau, A., Mahr, C., Skipper, E., Cossette, M., & Noly, P. (2021). Outcomes after Heart Transplantation and Total Artificial Heart Implantation: A Multicenter Study. The Journal of Heart and Lung Transplantation, 40(4), S184–S185. doi:10.1016/j.healun.2021.01.540

Büyükatalay, Z. Ç., Agha Oghali, A. M. N., Kendirli, T., Can, Ö. S., Uçar, T., Akar, A. R., & Meço, C. (2021). First Reported Cochlear Implantation in a Child with Total Artificial Heart. Experimental and Clinical Transplantation, 19(12), 1352–1355. doi:10.6002/ect.2019.0304

Copeland, J., Langford, S., Giampietro, J., Arancio, J., & Arabia, F. (2021). Total Artificial Heart Update. Surgical Technology Online. doi:10.52198/21.sti.38.cv1449

Le Picault, B., David, C.-H., Alexandre, P.-L., Lenoble, C., Bizouarn, P., Lepoivre, T., Groleau, N., Rozec, B., Desal, H., Roussel, J.-C., & Sénage, T. (2021). Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation. Bioengineering, 8(9), 126. doi:10.3390/bioengineering8090126

Woods, R. K., Kindel, S., Mitchell, M. E., Hraska, V., & Niebler, R. A. (2020). Evolving understanding of total artificial heart support of young infants and children. The Journal of Thoracic and Cardiovascular Surgery, 159(3), 1075–1082. doi:10.1016/j.jtcvs.2019.09.063

Beasley, G. S., Allen, K., Pahl, E., Jackson, L., Eltayeb, O., Monge, M., Backer, C., & Thrush, P. (2020). Successful Bridge to Transplant in a Pediatric Patient Using the SynCardia 50 cc Total Artificial Heart. ASAIO Journal, 66(2), e33. doi:10.1097/MAT.0000000000000968

Gregoric, I. D., Akay, M. H., Salas de Armas, I. A., Patel, M. K., Nathan, S. S., Akkanti, B., Stojanovic, S., Radovancevic, R., & Kar, B. (2020). Total Artificial Heart Salvage of a Heterotopic Heart Transplant Patient. ASAIO Journal, 66(1), e15–e18. doi:10.1097/mat.0000000000000962

Arabía, F. A. (2020). Cardiac replacement: total artificial heart. Annals of Cardiothoracic Surgery, 9(2), 68. Cardiology in Review: November/December 2020 - Volume 28 - Issue 6 - p 275-282 doi: 10.1097/CRD.00000000000003229

Thangappan, K., Ashfaq, A., Villa, C., & Morales, D. L. S. (2020). The total artificial heart in patients with congenital heart disease. Annals of Cardiothoracic Surgery, 9(2), 89–97. doi:10.21037/acs.2020.02.08

Morshuis, M., Rojas, S. V., Hakim-Meibodi, K., Razumov, A., Gummert, J. F., & Schramm, R. (2020). Heart transplantation after SynCardia® total artificial heart implantation. Annals of Cardiothoracic Surgery, 9(2), 98–103. doi:10.21037/acs.2020.03.12

Villa, C. R., Moore, R. A., Morales, D. L., & Lorts, A. (2020). The total artificial heart in pediatrics: outcomes in an evolving field. Annals of Cardiothoracic Surgery, 9(2), 104–109. doi:10.21037/acs.2020.02.15

Jaquiss, R. D. B., & Woods, R. K. (2020). Insertion of the total artificial heart in the Fontan circulation . Annals of Cardiothoracic Surgery, 9(2), 134–140. doi:10.21037/acs.2020.03.11

Lebreton, G., Kalbani, H. A., Juvin, C., & Leprince, P. (2020). Transitioning to total artificial heart for patients supported with short term mechanical circulatory devices. Annals of Cardiothoracic Surgery, 9(2), 141–143. doi:10.21037/acs.2020.03.06

David, C.-H., Lacoste, P., Nanjaiah, P., Bizouarn, P., Lepoivre, T., Michel, M., Pattier, S., Toquet, C., Périgaud, C., Mugniot, A., Al Habash, O., Petit, T., Groleau, N., Rozec, B., Trochu, J. N., Roussel, J. C., & Sénage, T. (2020). A heart transplant after total artificial heart support: initial and long-term results. European Journal of Cardio-Thoracic Surgery, 58(6), 1175–1181. doi:10.1093/ejcts/ezaa261

Woods, R. K., Niebler, R., Kindel, S., Troshynski, T., Joyce, L. D., & Hraska, V. (2019). A new method for implanting a total artifical heart in the patient with a Fontan circulation. The Journal of Thoracic and Cardiovascular Surgery, 157(1), 353–355. doi:10.1016/j.jtcvs.2018.08.082

Arabía FA, Cantor RS, Koehl DA, et al. Interagency registry for mechanically assisted circulatory support report on the total artificial heart. The Journal of Heart and Lung Transplantation. 2018;37(11):1304-1312. doi:10.1016/j.healun.2018.04.004.

From the *Division of Cardiothoracic Transplant and Assist Devices. (n.d.). Use of remote pulmonary artery pressure monitoring... : Asaio Journal. LWW. https://journals.lww.com/asaiojournal/Fulltext/2018/07000/Use_of_Remote_Pulmonary_Artery_Pressure_Monitoring.29.aspx
Mikail P;Crosby JR;Slepian MJ;Smith R;Khalpey Z; (n.d.-a). LVAD pulsatility assesses cardiac contractility: In vitro model utilizing the total artificial heart and mock circulation. ASAIO journal (American Society for Artificial Internal Organs : 1992). https://pubmed.ncbi.nlm.nih.gov/30074963/

Villa CR, Morales DLS. The Total Artificial Heart in End-Stage Congenital Heart Disease. Frontiers in Physiology. 2017;8:131. doi:10.3389/fphys.2017.00131.
Wells D, Villa CR, Morales DLS. The 50/50 cc Total Artificial Heart Trial: Extending the Benefits of the Total Artificial Heart to Underserved Populations. Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual. 2017;20:16-19. doi:10.1053/j.pcsu.2016.09.004.
Ferng AS, Oliva I, Jokerst C, et al. Translation of First North American 50 and 70 cc Total Artificial Heart Virtual and Clinical Implantations: Utility of 3D Computed Tomography to Test Fit Devices. Artificial Organs. 2017;41(8):727-734. doi:10.1111/aor.12854.
Morales DLS, Lorts A, Rizwan R, Zafar F, Arabia FA, Villa CR. Worldwide Experience with the Syncardia Total Artificial Heart in the Pediatric Population. ASAIO Journal. 2017;63(4):518-519. doi:10.1097/mat.0000000000000504.
Yaung J, Arabia FA, Nurok M. Perioperative Care of the Patient With the Total Artificial Heart. Anesthesia & Analgesia. 2017;124(5):1412-1422. doi:10.1213/ane.0000000000001851.
Crosby JR, Decook KJ, Tran PL, et al. A Physical Heart Failure Simulation System Utilizing the Total Artificial Heart and Modified Donovan Mock Circulation 2016;41(7):E52–E65. doi:10.1111/aor.12808.

Morales D, Rizwan R, Zafar F, et al. The Worldwide Experience of SynCardia Total Artificial Heart in Patients with Congenital Heart Disease. The Journal of Heart and Lung Transplantation. 2016;35(4):S162–S163. doi:10.1016/j.healun.2016.01.452.

Ruzza A, Czer L, Robertis MD, et al. Total Artificial Heart as Bridge to Heart Transplantation in Chagas Cardiomyopathy: Case Report. Transplantation Proceedings. 2016;48(1):279-281. doi:10.1016/j.transproceed.2015.12.017.

Mokadam NA, Mahr C. Victims of Our Own Success…and Failure. ASAIO Journal. 2016;62(1):1-2. doi:10.1097/mat.0000000000000310.

Devaney EJ. The total artificial heart in pediatrics: Expanding the repertoire. The Journal of Thoracic and Cardiovascular Surgery. 2016;151(4). doi:10.1016/j.jtcvs.2015.12.039.

Gerosa G, Gallo M, Bottio T, Tarzia V. Successful heart transplant after 1374 days living with a total artificial heart. European Journal of Cardio-Thoracic Surgery. 2016;49(4). doi:10.1093/ejcts/ezv469.

Ihnken KA, Ramzy D, Esmailian F, Trento A, Arabía FA. Surgical Technique to Facilitate Explantation of Mechanical Circulatory Support Devices (MCS). ASAIO Journal. 2016;62(2):211-213. doi:10.1097/mat.0000000000000318.

Ramirez A, Riley JB, Joyce LD. Multi-Targeted Antithrombotic Therapy for Total Artificial Heart Device Patients. The Journal of ExtraCorporeal Technology. 2016;48:27-34.

Dimitriou AM, Dapunt O, Knez I, Wasler A, Oberwalder P, Koerfer R, Tenderich G, Spiliopoulos S. Liver Failure in Total Artificial Heart Therapy. Journal of Thoracic Disease. 2016;8(7):1546-1549.

Shah KB, Thanavaro KL, Tang DG, et al. Impact of INTERMACS Profile on Clinical Outcomes for Patients Supported With the Total Artificial Heart. Journal of Cardiac Failure. 2016;22(11):913-920. doi:10.1016/j.cardfail.2016.04.016.

Shah R, Patel DB, Mankad AK, et al. Pulmonary Hypertension After Heart Transplantation in Patients Bridged with the Total Artificial Heart. ASAIO Journal. 2016;62(1):69-73. doi:10.1097/mat.0000000000000298.

Ryan, T. D., Jefferies, J. L., Zafar, F., Lorts, A., & Morales, D. L. S. (2015). The Evolving Role of the Total Artificial Heart in the Management of End-Stage Congenital Heart Disease and Adolescents. ASAIO Journal, 61(1), 8–14. doi:10.1097/mat.0000000000000156

Samak, M., Fatullayev, J., Sabashnikov, A., Zeriouh, M., Rahmanian, P. B., Choi, Y.-H., Wippermann, J., Wahlers, T., Schmack, B., Ruhparwar, A., Dohmen, P. M., Karck, M., Popov, A.-F., Simon, A. R., & Weymann, A. (2015). Past and Present of Total Artificial Heart Therapy: A Success Story. Medical Science Monitor Basic Research, 21, 183–190. doi:10.12659/msmbr.895418

‌Spiliopoulos, S., Dimitriou, A. M., Guersoy, D., Koerfer, R., & Tenderich, G. (2015). Expanding Applicability of Total Artificial Heart Therapy: The 50-cc SynCardia Total Artificial Heart. The Annals of Thoracic Surgery, 100(3), e55–e57. doi:10.1016/j.athoracsur.2015.04.010

Si, M.-S., Pagani, F. D., & Haft, J. W. (2016). Use of the total artificial heart as a bridge to transplant in a 13-year-old with congenitally corrected transposition of the great arteries. The Journal of Thoracic and Cardiovascular Surgery, 151(4), e71–e73. doi:10.1016/j.jtcvs.2015.11.049

Adachi, I., & Morales, D. S. L. (2014). Implantation of Total Artificial Heart in Congenital Heart Disease. Journal of Visualized Experiments, 89. https://doi.org/10.3791/51569

Spiliopoulos, S., Koerfer, R., & Tenderich, G. (2014). A first step beyond traditional boundaries: destination therapy with the SynCardia total artificial heart. Interactive CardioVascular and Thoracic Surgery, 18(6), 855–856. https://doi.org/10.1093/icvts/ivu065

El Banayosy, A., Kizner, L., Arusoglu, L., Morshuis, M., Brehm, C., Koerfer, R., Schuermann, C., Smith, R. G., Copeland, J. G., & Slepian, M. J. (2014). Home Discharge and Out-of-Hospital Follow-Up of Total Artificial Heart Patients Supported by a Portable Driver System. ASAIO Journal, 60(2), 148–153. https://doi.org/10.1097/mat.0000000000000046

Tang, D. G., Shah, K. B., Hess, M. L., & Kasirajan, V. (2014). Implantation of the Syncardia Total Artificial Heart. Journal of Visualized Experiments, 89. https://doi.org/10.3791/50377

‌Parker, M. S., Fahrner, L. J., Deuell, B. P. F., Olsen, K. M., Kasirajan, V., Shah, K. B., Medina, A. E., Doolin, K. R., de Groot, P. A., & Goodman, W. C. (2014). Total Artificial Heart Implantation: Clinical Indications, Expected Postoperative Imaging Findings, and Recognition of Complications. American Journal of Roentgenology, 202(3), W191–W201. https://doi.org/10.2214/ajr.13.11066

Torregrossa, G., Morshuis, M., Varghese, R., Hosseinian, L., Vida, V., Tarzia, V., Loforte, A., Duveau, D., Arabia, F., Leprince, P., Kasirajan, V., Beyersdorf, F., Musumeci, F., Hetzer, R., Krabatsch, T., Gummert, J., Copeland, J., & Gerosa, G. (2014). Results With Syncardia Total Artificial Heart Beyond 1 Year. ASAIO Journal, 60(6), 626–634. https://doi.org/10.1097/mat.0000000000000132

Torregrossa, G., Anyanwu, A., Zucchetta, F., & Gerosa, G. (2014). SynCardia: the total artificial heart. Annals of cardiothoracic surgery, 3(6), 612–620. https://doi.org/10.3978/j.issn.2225-319X.2014.11.07

Arabia, F. A., & Moriguchi, J. D. (2014). Machines versus medication for biventricular heart failure: focus on the total artificial heart. Future Cardiology, 10(5), 593–609. https://doi.org/10.2217/fca.14.47

Thanavaro, K. L., Tang, D. G., Kasirajan, V., & Shah, K. B. (2014). Clinical Indications for Implantation of the Total Artificial Heart. ASAIO Journal, 60(5), 594–596. https://doi.org/10.1097/mat.0000000000000111

Gerosa, G., Scuri, S., Iop, L., & Torregrossa, G. (2014). Present and future perspectives on total artificial hearts. Annals of cardiothoracic surgery, 3(6), 595–602. https://doi.org/10.3978/j.issn.2225-319X.2014.09.05

Copeland J. G. (2013). SynCardia Total Artificial Heart: update and future. Texas Heart Institute journal, 40(5), 587–588. PMID: 24391330; PMCID: PMC3853833

Copeland, J., Copeland, H., Nolan, P., Gustafson, M., Slepian, M., & Smith, R. (2013). Results with an Anticoagulation Protocol in 99 SynCardia Total Artificial Heart Recipients. ASAIO Journal, 59(3), 216–220. doi:10.1097/mat.0b013e318288a390

Loforte, A., Stepanenko, A., Potapov, E. V., Musumeci, F., Dranishnikov, N., Schweiger, M., Montalto, A., Pasic, M., Weng, Y., Dandel, M., Siniawski, H., Kukucka, M., Krabatsch, T., & Hetzer, R. (2013). Temporary Right Ventricular Mechanical Support in High-Risk Left Ventricular Assist Device Recipients Versus Permanent Biventricular or Total Artificial Heart Support. Artificial Organs, 37(6), 523–530. doi:10.1111/aor.12038

Quader, M. A., Tang, D., Katlaps, G., Shah, K. B., & Kasirajan, V. (2013). Total artificial heart for patients with allograft failure. The Journal of Thoracic and Cardiovascular Surgery, 145(2), e21–e23. doi:10.1016/j.jtcvs.2012.10.050

Ashfaq, A., Jaroszewski, D. E., Pajaro, O. E., & Arabia, F. A. (2013). The role of the total artificial heart in the treatment of post–myocardial infarction ventricular septal defect. The Journal of Thoracic and Cardiovascular Surgery, 145(2), e25–e26. doi:10.1016/j.jtcvs.2012.11.018

Kirsch, M. E. W., Nguyen, A., Mastroianni, C., Pozzi, M., Léger, P., Nicolescu, M., Varnous, S., Pavie, A., & Leprince, P. (2013). SynCardia Temporary Total Artificial Heart as Bridge to Transplantation: Current Results at La Pitié Hospital. The Annals of Thoracic Surgery, 95(5), 1640–1646. doi:10.1016/j.athoracsur.2013.02.036

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